Products

 Pravastatin Sodium
 Mevastatin/Compactin
 Mycophenolic Acid

Contact: Mr. Kang / Ms. Lin
TEL:  0086-763-3865280
 0086-763-3865278
FAX:  0086-763-3366526
ADD:  Renmin One Road 
 Qingyuan Guangdong
 China
P.C.:  511515

 

 

 

 

Intermediate

Common Name:Mevastatin/Compactin

QUALITY STANDARD:In-house specifications (content: more than 95.0%)

CAS Registry Number:73573-88-3

Molecular Formula:C23H34O5

Molecular Mass:390.51

Structural Formula









Chemical  Name: 2-Methyl-butanoic acid [1S-[1-alpha(R*),7-beta,8-beta(2S*,4S*), 8a-beta]]-1,2,3,7, 8,8a-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy- 6-oxo-2H-pyran-2-yl)ethyl]-1 -naphthalenyl ester                                          

Therapeutic Category: Starting material used in the production of API Pravastatin Sodium

Mechanism of action: Compaction, also known as Mevastatin, is an inhibitor of HMG-CoA  reductase. Compactin functions by inhibiting the enzyme HMG-CoA reductase, an  enxyme involved in the biosynthenic pathway of cholesterol. Although Compactin  is active in lowering cholesterol levels in humans, a derivative of Compactin,  named Pravastatin, was found to be more efficacious in this function. Thus, generally  Compactin is used as a starting material of Pravastatin.
                 
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