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 Mycophenolic Acid

Contact: Mr. Kang / Ms. Lin
TEL:  0086-763-3865280
 0086-763-3865278
FAX:  0086-763-3366526
ADD:  Renmin One Road 
 Qingyuan Guangdong
 China
P.C.:  511515

 

 

 

 

Intermediate

Common Name:Mycophenolic Acid

Specifications:In-house specifications (Content: more than 95%)

Registry Number:24280-93-1

Molecular Formula:C17H20O6

Molecular Mass:320.34

Structural Formula

Chemical  Name:6-(1, 3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid
                     
Appearance: Off-white to yellowish crystalline powder
                     
Therapeutic Category:Mycophenolic acid (MPA) is marketed as the prodrug mycophenolate mofetil (MMF).
                     
Mechanism of action: Mycophenolic Acid (MPA) is a potent, selective, noncompetitive and reversible inhibitor of inosine monophosphate dehydrogenase(MPDH), the enzyme that controls the rate of synthesis of guanine monophosphate in the de novo pathway of purine synthesis used in the proliferation of B and T lymphocytes. Mycophenolate mofetil (MMF) is the 2-morpholinoethyl ester prodrug of MPA and is metabolized in the liver to the active moiety mycophenolic acid.
                 
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